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Daily Data InsightsChildhood cancer deaths in the United States have declined six-fold over the last seventy years

Childhood cancer deaths in the United States have declined six-fold over the last seventy years

This chart presents US cancer death rates in children under five years old, measured in reported annual death rates per 100,000 children. It consists of four graphs:

1. All Malignant Cancers Combined: This graph, shown in black, illustrates a decline in childhood cancer death rates from about 11 per 100,000 in 1950 to around 1.8 in 2021, indicating a six-fold decrease since the 1950s.
   
2. Leukemia: This graph shows a decrease from around 5 per 100,000 in 1950 to less than 1 in 2021, following a similar declining trend throughout the decades.

3. Brain and Nervous System Cancers: This chart shows some fluctuations but overall a decline from nearly 0.8 per 100,000 in 1950 to about 0.4 in 2021.

4. Lymphomas and Multiple Myeloma: This graph shows fluctuations and a decline from around 0.8 in the late 1950s to less than 0.2 by 2021.

The data is sourced from the WHO Mortality Database (2024), with a note indicating that figures may fluctuate year-by-year due to low numbers.

Childhood cancer deaths in the United States have fallen dramatically over time, as shown in the chart. It presents annual cancer death rates in children under five years old.

There has been a six-fold decline since the 1950s.

This progress reflects decades of collaboration between scientists, clinicians, and public health workers.

One major success story has been in treating acute lymphoblastic leukemia, a common form of leukemia in children: researchers identified genetic mutations that caused the disease, making it possible to develop targeted chemotherapy drugs that have greatly improved survival. Surgeries, bone marrow transplants, and other treatments have also played a role.

We’ve also seen big improvements for other blood cancers, such as lymphomas and multiple myeloma, though progress has been slower for cancers of the brain and nervous system.

Explore more data on our page on cancer

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